Bismuth Science and Biomedical Materials Team

 

Overview

The Bismuth Science and Biomedical Materials Team focuses on the application of bismuth and related nanomaterials in the biomedical field, especially nano diagnosis and treatment, anti-cancer drugs, and antibacterial materials. The team members have published more than 300 SCI papers (more than 60 papers in JCR Q1) in Chem. Rev., Trend. Biotechnol., Biotechnol. Adv., NPG Asia Material., ACS Appl. Mater. Interf., Biosensor. Bioelectron., Nanoscale, and other journals, and authorized 12 invention patents and transferred 2 of them. At present, the team has published more than 40 SCI papers related to bismuth, including 4 ESI highly cited papers, 2 Hot papers, 2 cover articles. The Bismuth Science and Biomedical Materials Team is led by Professor Miao Yuqing, with 1 professor, 6 associate professors, 4 lecturers, and more than 40 doctoral and master students.

 

Team leader

·         Professor MIAO Yuqing,

Dean of Institute of Bismuth Science, USST;

Director of Institute of Applied Chemistry, USST;

Fellow of the Royal Society of Chemistry (FRSC)

Member of Chemical Sensors Branch, Chinese Society of Instrumentation

Editorial Board Member of Frontiers in Chemistry (IF 5.221)

 

Members

·         Associate Professor OUYANG Ruizhuo, Chairman of Department of Chemistry, School of Materials and Chemistry, USST

·         Associate Professor LI Yuhao

·         Associate Professor WANG Shige

·         Associate Professor GUO Ning

·         Associate Professor AN Yarui

·         Lecturer XIN Yanmei

·         Lecturer YAO Congfei

·         Lecturer YUE Bingbing

·         Lecturer WANG Shixia

 

Research Fields

·         Biomedical applications (Focus): nano diagnosis and treatment, anticancer drugs, antibacterial materials, hydrogen biomedicine, nano catalytic medicine

·         Luminescent materials and applications: fluorescent materials, temperature sensors

·         Photo/electrocatalysis: hydrogen production, fuel cells, pollutant degradation

 

Important research and development projects

·           National Natural Science Foundation of China, 2012-2014 (41103002)

·           National Natural Science Foundation of China, 2015-2017 (21401130)

·           National Natural Science Foundation of China, 2016-2018 (21501121）

·           Special project of China Postdoctoral Science Foundation（2016T90376）

·           Natural Science Foundation of Shanghai（19ZR1434700）

·           Shanghai Sailing Program, 2020-2023 (20YF1432600)

·           Shanghai Sailing Program, 2020-2023 (20YF1432500)

·           Foundation of State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, 2021-2022 (2021-K50)

 

Important papers and publications

·         Yuqing Miao*, Nongyue He and Jun-Jie Zhu. History and new developments of assays for cholinesterase activity and inhibition. Chemical Reviews, 2010, 110, 5216-5234.

·         Dongling Jia*, Yifan Zhang, Xue Zhang, Peiying Feng, Lin Yang, Ruonan Ning, Hongzhi Pan* and Yuqing Miao*, Facile fabrication of Bi nanoparticle-decorated g-C₃N₄ photocatalysts for effective tetracycline hydrochloride degradation: environmental factors, degradation mechanism, pathways and biotoxicity evaluation, Environmental Science: Nano, 2021, 8, 415-431. (Back cover paper)

·         Ruizhuo Ouyang, Penghui Cao, Pengpeng Jia, Hui Wang, Tianyu Zong, Chenyu Dai, Jie Yuan, Yuhao Li, Dong Sun, Ning Guo, Yuqing Miao*, Shuang Zhou*. Bistratal Au@Bi₂S₃ Nanobones for Excellent NIR-Triggered/Multimodal Imaging-Guided Synergistic Therapy for Liver Cancer. Bioactive Materials, 2021, 6, 386-403.

·         Jie Liu, Jing Zhang, Yuqing Miao, Yun Sun,* Yuhao Li*, et al. Tumor Microenvironment Modulation Platform Based on Composite Biodegradable Bismuth–Manganese Radiosensitizer for Inhibiting Radioresistant Hypoxic Tumors, Small, 2021, 17, 2101015.

·         Yongtian Liu, Jing Zhang, Yuqing Miao, Yun Sun*, Yuhao Li*, et al. Biodegradable BiOCl Platform for Oxidative Stress Injury–Enhanced Chemodynamic/Radiation Therapy of Hypoxic Tumors, Acta Biomater., 2021, 129, 280-292.

·         Yong Deng, Yun Sun*, Yuhao Li*, et al. Dual-light triggered metabolizable nano-micelles for selective tumor-targeted photodynamic/hyperthermia therapy, Acta Biomater., 2021, 119, 323-336.

·           Yao Wang, Ning Guo*, et al. A solid-solution modulation strategy in trivalent bismuth-doped gallate phosphors for single substrate tunable emission. Dalton Transactions, 2021, 50, 12592-12606.

·           Qincan Ma, Ning Guo*, et al. Constructing a Model for Tuning the Thermal Quenching Properties of Bismuth-Doped Phosphors by Energy-Gap Modulation. Journal of Physical Chemistry C, 2021, 125, 20717-20726.

·           Qincan Ma, Ning Guo*, et al. Preparation of zero-thermal-quenching tunable emission bismuth-containing phosphors through the topochemical design of ligand configuration. Inorganic Chemistry Frontiers, 2021, 8, 4072-4085.

·           Yao Wang, Ning Guo*, et al. Adjustable photoluminescence of Bi³⁺ and Eu³⁺ in solid solution constructed by isostructural end components through composition and excitation-driven strategy. Chemical Engineering Journal, 2021, 421, 127735.

·           Yao Wang, Ning Guo*, et al. A colorimetric optical thermometry of host-sensitized Pr3+-doped niobate phosphors based on electronic-rich-site strategy. Dalton Transactions, 2021, 50, 7026-7040.

·           Xiaoyan Chen, Lin Song, Guanyang Zhu, Jing Ma, Ajing Xu, Wenya Zhao, Yingying Gu, Yarui An* and Yuqing Miao, A novel site-induced biomolecule anchoring strategy based on solid superacid ZrO₂/SO₄^2- for fabricating label-free IgG electrochemical immunosensors. New J. Chem., 2021, 45, 10850–10856

·         Lin Yang, Yanmei Xin*, Congfei Yao, and Yuqing Miao*, In situ preparation of Bi₂WO₆/CAU-17 photocatalyst with excellent photocatalytic activity for dye degradation. J Mater Sci: Mater Electron, 2021, 32, 13382-13395.

·           Panbing Hu, Congfei Yao*, Lin Yang, Yanmei Xin, Yuqing Miao. Boosted photodegradation of tetracycline hydrochloride over Z-scheme MIL-88B(Fe)/Bi₂WO₆ composites under visible light [J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2021, 627, 127248.

·           Jian Gu, Bingbing Yue*, Glib V. Baryshnikov, Zhongyu Li, Man Zhang, Shen Shen, Hans Ågren, Liangliang Zhu*, Visualizing Material Processing via Photoexcitation-Controlled   Organic-Phase Aggregation-Induced Emission, Research 2021, 2021, 9862093.

·           Shixia Wang*, Tianyi Hu, Meng Yang. Study on Preparation of Ag-doped ZnO Nanomaterials and Phase Transition at High Pressure Using Diamond Anvil Cell and Raman Spectra. Spectroscopy and Spectral Analysis, 2021(41), 02: 484-488.

·           Shixia Wang*, Kaijie Lu, Wang Teng, et al. A method for Isotope Exchange Kinetics in Mineral-Water System-an in-situ Study on Oxygen Isotope Exchange in Na₂CO₃-H₂O System[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 241:118648.

·         Jing Zhang, Yun Sun*, Yuhao Li*, et al. Nanozyme-incorporated biodegradable bismuth mesoporous radiosensitizer for tumor microenvironment-modulated hypoxic tumor thermoradiotherapy, ACS Appl. Mater. Interfaces, 2020, 12, 57768-57781.

·         Jie Liu, Yun Sun*, Yuhao Li*, et al. X-ray and NIR light dual-triggered mesoporous upconversion nanophosphor/Bi heterojunction radiosensitizer for highly efficient tumor ablation, Acta Biomater., 2020, 113, 570-583.

·         Guangcong Zhang, Jie Liu, Jimin Zhu*, Shuqiang Wen*, Yuhao Li*, et al. Bismuth-based mesoporous nanoball carrying sorafenib for computed tomography imaging and synergetic chemoradiotherapy of hepatocellular carcinoma, Adv. Healthc. Mater., 2020, 2000650.

·         Xiaojia Qin, Jie Liu, Yuhao Li*, Yingjian Zhang, Yun Sun*, et al. Mesoporous Bi-containing radiosensitizer loading with DOX to repolarize tumor-associated macrophages and elicit immunogenic tumor cell death to inhibit tumor progression, ACS Appl. Mater. Interfaces, 2020, 12, 31225-31234.

·         Xiangnan Yu, Yong Deng, Yuhao Li*, Jimin Zhu*, et al. Sorafenib-conjugated zinc phthalocyanine-based nanocapsule for trimodal therapy in an orthotopic hepatocellular carcinoma xenograft mouse model, ACS Appl. Mater. Interfaces, 2020, 12, 17193-17206.

·         Wei Yue, Meifeng Hao, Bin Yu, Ruizhuo Ouyang, Yuqing Miao. Using non-combustion explosion in H₂O/DMF to synthesize 3D structure of ultrathin Bi nanofilm with high catalytic activity for p-nitrophenol reduction. Nanotechnology, 2020, 31, 145717.

·           Congfei Yao, Yucui Hou, Ying Sun, Weize Wu*, Shuhang Ren, Hui Liu. Extraction of aromatics from aliphatics using a hydrophobic dicationic ionic liquid adjusted with small-content water. Separation and Purification Technology. 2020, 236, 116287.

·         Jie Liu, Yuhao Li*, Yuqing Miao* and Yun Sun*, et al. Ultrafast synthesizing bismuth mesoporous nanolitchi radiosensitizer loading high dose DOX for CT-guided enhanced chemoradiotherapy, ACS Appl. Mater. Interfaces, 2019, 11, 42932-42942. (Cover paper)

·         Yuhao Li*, Yuqing Miao, et al. An AEE-active probe combined with cyanoacrylate fuming for a high resolution fingermark optical detection, Sensor. Actuat. B Chem., 2019, 283, 99-106.

·         Guanyang Zhu, Xiaodie Yin, Danli Jin, Bo Zhang, Yingying Gu, Yarui An*, Paper-based immunosensors: current trends in the types and applied detection techniques. TRAC-Trend. Anal. Chem. 2019, 111: 100-117.

·           Penghui Li, Yingying Gu*, et al. TiO₂-SnO₂/SO₄^2- mesoporous solid superacid decorated nickel-based material as efficient electrocatalysts for methanol oxidation reaction. Electrochimica Acta. 2019, 297: 864-871.

·         Bingbing Yue, Liyuan Yin, Wandong Zhao, Xiaoyong Jia, Mingjie Zhu, Bin Wu, Si Wu, Liangliang Zhu*, Chirality transfer in organogel-based nanofibers enabling wide-range naked-eye enantiodifferentiation, ACS Nano 2019, 09.

·         Bingbing Yue, Xin Jin, Pei Zhao, Mingjie Zhu, Liangliang Zhu*, Directed Self-Assembly of Templatable Block Copolymers by Easily Accessible Magnetic Control, Small 2019, 15, 1804572.

·         Yanmei Xin, Zhonghai Zhang, Photoelectrochemical stripping analysis. Anal Chem, 2018, 90, 1068-1071.

·         Mao Zhou, Ya Liu, Dejuan Fa, Lihong Qian, Yuqing Miao. Growth of radial microspheres of Ni-Co-O at porous Ti and its phosphorization for high efficient hydrogen evolution. Electrochim. Acta, 2018, 259, 329-337.

·           Congfei Yao, Yucui Hou, Weize Wu*, Shuhang Ren, Hui Liu. Imidazolium-based dicationic ionic liquids: Highly efficient extractants for separating aromatics from aliphatics. Green Chemistry. 2018, 20, 3101-3111.

·         Mao Zhou, Ruizhuo Ouyang, Yuhao Li, Yuqing Miao. 3D Microspheres organized from Ni-Mo-S nanoparticles in situ synthesized on porous Ti for hydrogen evolution electrocatalysis. Electrochim. Acta, 2017, 246, 9-16.

·         Ruizhuo Ouyang*, Yang Yang, Xiao Tong, Kai Feng, Yaoqin Yang, Huihong Tao, Xiaoshen Zhang, Tianyu Zong, Penghui Cao, Fei Xiong, Ning Guo, Yuhao Li, Yuqing Miao *, Shuang Zhou *. Potent anticancer activity of a new bismuth (III) complex against human lung cancer cells, J. Inorg. Biochem., 2017, 168:18-26.

·         Yuhao Li*, Yun Sun*, Yuqing Miao, et al. A cation-exchange controlled core-shell MnS@Bi₂S₃ theranostic platform for multimodal imaging guided radiation therapy with hyperthermia boost, Nanoscale, 2017, 9, 14364-14375. (Back cover paper)

·         Yarui An*, Guanyang Zhu, Wenji Bi, Linlin Lu, Chongchong Feng, Zhiai Xu, Wen Zhang, Highly sensitive electrochemical immunoassay integrated with polymeric nanocomposites and enhanced SiO₂@Au core-shell nanobioprobes for SirT1 determination, Anal. Chim. Acta, 2017, 966(18), 54-61

·         Yanmei Xin, Zhenzhen Li, Wenlong Wu, Baihe Fu, Hongjun Wu, Zhonghai Zhang*. Recognition unit-free and self-cleaning photoelectrochemical sensing platform on TiO₂ nanotube photonic crystals for sensitive and selective detection of dopamine release from mouse brain. Biosens Bioelectron, 2017, 87, 396-403.

·         Yanmei Xin, Xiang Kan, Liyong Gan, Zhonghai Zhang*, Heterogeneous bimetallic phosphide/sulfide nanocomposite for efficient solar-energy-driven overall water splitting. ACS Nano, 2017, 11 (10), 10303-10312.

·         Yingying Gu*, Yang, Haihong, Yarui An*, A ternary nanocatalyst of Ni/Cr/Co oxides with high activity and stability for alkaline glucose electrooxidation. Electrochimica Acta. 2016, 192: 196-302.

·         Yuhao Li, Wei Feng*, Fuyou Li*, et al. Ultrasensitive near-infrared fluorescence-enhanced probe for in vivo nitroreductase imaging, J. Am. Chem. Soc., 2015, 137 (19), 6407-6416. (ESI high cited paper)

·         Mingshu Xiao, Rui Cheng, Meifeng Hao, Mao Zhou, and Yuqing Miao*. Onsite substitution synthesis of ultrathin Ni nanofilms loading ultrafine Pt nanoparticles for hydrogen evolution. ACS Appl. Mater. Interf. 2015, 7, 26101-26107

·         Mingshu Xiao, Dazhang Yang, Yuhua Yan, Yanping Tian, Mao Zhou, Meifeng Hao, Rui Cheng, Yuqing Miao*. Nanoplates and nanospheres of Co₃(VO₄)₂ as noble metal-free electrocatalysts for oxygen evolution. Electrochim. Acta. 2015, 180, 260-267

·         Mingshu Xiao, Yuqing Miao*, Yanping Tian, Yuhua Yan. Synthesizing nanoparticles of Co-P-Se compounds as electrocatalysts for the hydrogen evolution reaction. Electrochim. Acta. 2015, 165, 206-210

·         Mingshu Xiao*, Yanping Tian, Yuhua Yan, Kai Feng, Yuqing Miao*. Electrodeposition of Ni(OH)₂/NiOOH in the presence of urea for the improved oxygen evolution. Electrochim. Acta. 2015, 164, 196-202

·         Mingshu Xiao, Yuqing Miao*, Weiwei Li, Yang Yang, Xiaocai Liang, Onsite deposition of self-repairing biomimetic nanostructured Ni catalysts with improved electrocatalysis toward glycerol oxidation for H₂ production. Electrochim. Acta. 2015, 178, 209-216

·         Yuqing Miao, Lei Ouyang, Shilin Zhou, Lina Xu, Zhuoyuan Yang, Mingshu Xiao, Ruizhuo Ouyang, Electrocatalysis and electroanalysis of nickel, its oxides, hydroxides and oxyhydroxides toward small molecules. Biosens. Bioelectron. 2014, 53, 428-439

·         Yuqing Miao, Zhuoyuan Yang, Xiaoyan Liu, Lina Xu, Lei Ouyang, Yingying Gu, Haizhou Chang, Ruizhuo Ouyang*. Self-assembly of BiIII ultrathin Layer on Pt surface for non-enzymatic glucose sensing. Electrochim. Acta, 2013, 111, 621-626

·         Huihui Wang, Shilin Zhou, Zhigang Wang, Shanling Xu, Song Dong, Yuqing Miao. Electrochemical conversion of Ni(OH)₂ nanoparticle film into nickel hexacyanoferrate through a simple strategy of potential cycling. Electrochim. Acta, 2012, 74, 201-206

·         Ying Mu, Dongling Jia, Yayun He, Yuqing Miao*, Hai-Long Wu. Nano NiO modified non-enzymatic glucose sensors with enhanced sensitivity through an electrochemical process strategy at high potential. Biosens. Bioelectron. 2011, 26, 2948-2952

·         Ruizhuo Ouyang, Jianping Lei, Huanxian Ju*, Yadong Xue. A molecularly imprinted copolymer designed for enantioselective recognition of glutamic acid. Adv. Funct. Mater., 2007, 17(16), 3223-3230.

 

Important patents and proprietary rights

·           China Patent, ZL 201910745679.X, 2021

·           China Patent, ZL 201810968423.0, 2021

·           China Patent, ZL201810592821, 2018

·           China Patent, ZL201610980169.7, 2016

·           China Patent, ZL 200410016752.3, 2004

·           China Patent, ZL 200410024876.6, 2004

 

Honors and awards 

·           2020: Third Prize of Teaching Competition for Young College Teachers in Shanghai (Yuhao Li)

·           2020: Second Prize of USST Teaching Skills Competition (Yuhao Li)

·           2019: The second Award for Micro Teaching Achievement, USST (Shixia Wang)

·           2018: Second Prize of USST Young Teachers Teaching Competition (Yuhao Li)

·           2017: The second Award for Teaching Achievement, USST (Shixia Wang)

·           2016: Award for Advanced Career Guide Teacher of Postgraduates, USST (Shixia Wang)

 

Activities in professional associations

·           2015-: Fellow of the Royal Society of Chemistry, FRSC （Yuqing Miao）

·           Committee member of Biochemical and Biotechnological Drug Committee of Shanghai Pharmaceutical Society (Yuhao Li, 2020-)

·           Committee member of Smart Medical Diagnosis Committee of Shanghai Biomedical Engineering Society (Yuhao Li, 2021-)

·           2018-: Official reviewer for Acta Geologica Sinica (Shixia Wang)

·           2017-: Being University Psychological Counseling Association member in Shanghai. (Shixia Wang)

·           2016-: Getting the certificate of University of Psychological consultant in Shanghai. (Shixia Wang)

 

 

Contact us

·           E-mail: yqmiao@usst.edu.cn (Yuqing Miao)

yhli@usst.edu.cn (Yuhao Li)

anyarui@usst.edu.cn (Yarui An)

guoning@usst.edu.cn (Ning Guo)

yygu@usst.edu.cn (Yinyin Gu)

wangshixia@usst.edu.cn (Shixia Wang)

yanmeixin@usst.edu.cn (Yanmei Xin)

congfeiyao@usst.edu.cn (Congfei Yao)